Mattonen Lab

Principal Investigator
Dr. Sarah Mattonen, PhD is an Assistant Professor at Western University in the Department of Medical Biophysics with a cross-appointment in the Department of Oncology. She holds the inaugural Gerald C. Baines Research Chair for Translational Cancer Imaging. She is also a scientist at the London Health Sciences Centre Research Institute. She received her PhD in Medical Biophysics from Western University in 2016 and completed her postdoctoral training at Stanford University in the Department of Radiology in 2019. Her research interests include developing, evaluating, and translating quantitative image analysis tools to support diagnosis, treatment, and response assessment in oncology. Her laboratory develops tools in image segmentation, image feature extraction, and outcome modelling to correlate imaging features with clinical outcomes. These computational imaging models will assist clinicians in decision-making and allow for personalized medicine, with the goal of improving outcomes for cancer patients.

Current Students
Edward Wang, BASc,  is an MD/PhD candidate in the Department of  Medical Biophysics at Western University and is currently completing his PhD in between his medical studies. He graduated from the University of British Columbia in 2019 with a degree in Chemical and Biological Engineering. During his PhD, Edward is developing AI-assisted clinical tools for radiation treatment planning, and is supported by a Vanier scholarship.
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 Marcus Milantoni is currently a MSc student at Western University studying Medical Science with an Honours Specialization in Medical Physics (Clinical Physics Concentration). He recently completed his third-year thesis project on CT-Based Radiomic Models for Predicting Early vs. Locally Advanced Stages of Esophageal Adenocarcinoma. He will remain in the lab this year to continue his work and complete his fourth-year thesis.
Christine Santiago, BSc, is currently an MSc student in the Department of Medical Biophysics at Western University. She completed her BSc in Medical Physics at Toronto Metropolitan University in 2023. Her research focuses on using machine learning on CT and PET images to predict the risk of recurrence in early-stage lung cancer patients who have undergone surgery.

Former Students

Jaryd Christie, PhD, completed his CAMPEP PhD in the Department of Medical Biophysics at Western University in 2024. His research focused on the development of a multi-modality clinical decision-support system for risk stratification in non-small cell lung cancer. Dr. Christie is currently a Medical Physics Resident at Henry Ford Health.
Tricia Chinnery, PhD, completed her CAMPEP PhD in the Department of Medical Biophysics at Western University in 2024.  Her research involved predicting radiation replanning and toxicity outcomes to support personalized treatment in oropharyngeal cancer. Dr. Chinnery is currently a Medical Physics Resident at UC San Diego.
Lauren Zelko, MSc, completed her Masters in the Department of  Medical Biophysics at Western University in 2023. Her project involved developing a radiomics based machine learning model to predict local progression of non-spine bone metastases following stereotactic radiotherapy. She is currently working as a Research Assistant at Robarts Research Institute.
Our Affiliations and Funding Partners